The SEQDESIGN Procedure
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Overview
- Getting Started
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Syntax
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Details
Fixed-Sample Clinical Trials One-Sided Fixed-Sample Tests in Clinical Trials Two-Sided Fixed-Sample Tests in Clinical Trials Group Sequential Methods Statistical Assumptions for Group Sequential Designs Boundary Scales Boundary Variables Type I and Type II Errors Unified Family Methods Haybittle-Peto Method Whitehead Methods Error Spending Methods Acceptance (beta) Boundary Boundary Adjustments for Overlapping Lower and Upper beta Boundaries Specified and Derived Parameters Applicable Boundary Keys Sample Size Computation Applicable One-Sample Tests and Sample Size Computation Applicable Two-Sample Tests and Sample Size Computation Applicable Regression Parameter Tests and Sample Size Computation Aspects of Group Sequential Designs Summary of Methods in Group Sequential Designs Table Output ODS Table Names Graphics Output ODS Graphics Acknowledgments
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Examples
Creating Fixed-Sample Designs Creating a One-Sided O’Brien-Fleming Design Creating Two-Sided Pocock and O’Brien-Fleming Designs Generating Graphics Display for Sequential Designs Creating Designs Using Haybittle-Peto Methods Creating Designs with Various Stopping Criteria Creating Whitehead’s Triangular Designs Creating a One-Sided Error Spending Design Creating Designs with Various Number of Stages Creating Two-Sided Error Spending Designs with and without Overlapping Lower and Upper beta Boundaries Creating a Two-Sided Asymmetric Error Spending Design with Early Stopping to Reject H0 Creating a Two-Sided Asymmetric Error Spending Design with Early Stopping to Reject or Accept H0
- References
| ODS Graphics |
Statistical procedures use ODS Graphics to create graphs as part of their output. ODS Graphics is described in detail in Chapter 21, Statistical Graphics Using ODS.
Before you create graphs, ODS Graphics must be enabled (for example, with the ODS GRAPHICS ON statement). For more information about enabling and disabling ODS Graphics, see the section Enabling and Disabling ODS Graphics in Chapter 21, Statistical Graphics Using ODS.
The overall appearance of graphs is controlled by ODS styles. Styles and other aspects of using ODS Graphics are discussed in the section A Primer on ODS Statistical Graphics in Chapter 21, Statistical Graphics Using ODS.
PROC SEQDESIGN assigns a name to each graph it creates. You can use these names to reference the graphs when using ODS. To request these graphs, ODS Graphics must be enabled and you must specify the options indicated in Table 80.13.
ODS Graph Name |
Plot Description |
Option |
|---|---|---|
ASNPlot |
Average sample numbers |
PLOTS=ASN |
BoundaryPlot |
Detailed boundary values |
PLOTS=BOUNDARY |
CombinedBoundaryPlot |
Boundary values |
PLOTS=COMBINEDBOUNDARY |
ErrSpendPlot |
Error spending |
PLOTS=ERRSPEND |
PowerPlot |
Power curves |
PLOTS=POWER |