The FAMILY Procedure
| Creating Allelic Transmission Scores |
Abecasis, Cookson, and Cardon (2000) define a pair of orthogonal allelic transmission scores, 
and 
, the expected genotype and deviate, respectively, for each individual at each marker. To create these scores, the genotype in terms of allele 
must first be defined as 
for individual 
, where 
represents the number of alleles that the genotype comprises. For any founder , an individual whose parents are not observed, in the sample, these scores are defined as 
and 
. Otherwise, let 
and 
be the respective indices of the mother and father of individual . Then for any nonfounder, assuming scores for an individual’s ancestors are calculated before his or her own,
 |
where 
, and then 
. These scores are calculated for all alleles at the markers specified in the VAR statement and are included in the OUTQ= data set.