The ALLELE Procedure
Measures of Marker Informativeness
Polymorphism Information Content
The polymorphism information content (PIC) measures the probability of differentiating the allele transmitted by a given parent to its child given the marker genotype of father, mother, and child (Botstein et al. 1980). It is computed as
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Heterozygosity
The heterozygosity, sometimes called the observed heterozygosity, is simply the proportion of heterozygous individuals in the data set and is calculated as
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Allelic Diversity
The allelic diversity, sometimes called the expected heterozygosity, is the expected proportion of heterozygous individuals in the data set when HWE holds. It is calculated as
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