Special Topic: Performance Considerations

Here are some best practice recommendations:
  • You should first run the SAS Clinical Standards Toolkit validation on a subset of source data to identify general process problems, missing or inconsistent process control metadata, and common (and perhaps correctable) data errors.
  • You should subset the SAS Clinical Standards Toolkit standard-specific Validation Master data set to remove duplicate checks. For example, CDISC SDTM 3.1.1 Janus checks are generally duplicates of WebSDM checks with occasionally different resultseverity values.
  • You should be toggled off the _cstDebug option, except for when you want to debug specific program errors to avoid exceeding the SAS log-size limitations or to avoid generating large SAS log files.
  • You should run in batch or using PROC PRINTTO any SAS Clinical Standards Toolkit validation process that involves a large number of checks. This is also true for a SAS Clinical Standards Toolkit validation process that is run with the _cstDebug option toggled on. Doing so avoids exceeding the SAS log-size limitations.