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The SEQTEST Procedure

Analysis after a Sequential Test

At the end of a trial, the hypothesis is either rejected or accepted. But the -value, median, and confidence limits depend on the ordering the sample space , where is the stage number and is the standardized statistic.

Following the notations used in Jennison and Turnbull (2000, pp. 179–180), if has a higher order or more extreme than . Then for a given ordering, the -value, median, and confidence limits associated with the observed statistics can be derived.

-value

With the observed pair of statistics when the trial is stopped, a one-sided upper -value is computed as

     

A one-sided lower -value is computed as

     

A two-sided -value is twice the smaller of the lower and upper -values.

Median Unbiased Estimate

With the observed pair , a median unbiased estimate is computed from

     

Confidence Limits

With the observed pair , a lower confidence limit for ,   , is computed from

     

Similarly, an upper confidence limit for ,   , is computed from

     
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