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The PHREG Procedure

Modified Score Statistic

Let  \bld{U}_0 be the n×p matrix of efficient scores and  \bld{I}_0be the p×p information matrix, both evaluated at  {\beta}=\bld{0}; let  \bld{1} be a column n-vector of 1's. Let \hat{{\beta}}_1 be the one-step estimate of {\beta}; that is,
\hat{{\beta}}_1=\bld{I}_0^{-1} (\bld{U}_0'\bld{1})
the covariance matrix is estimated by  \hat{\bld{V}}({\beta}_1)=\bld{I}_0^{-1}.

The score statistic for testing H0:{\beta}= \bld{0} can be expressed as a Wald test statistic (Therneau and Grambsch [2000]):

(\bld{U}'_0\bld{1})' \bld{I}_0^{-1} (\bld{U}_0'\bld{1}) &=& [\bld{I}_0^{-1} ... ...d{1})] \ &=& \hat{{\beta}}_1' [\hat{\bld{V}}({\beta}_1)]^{-1} \hat{{\beta}_1}

The modified score test statistic for testing H0:{\beta}= \bld{0}is obtained by replacing  \hat{\bld{V}}({\beta}_1) in the score statistic by the robust sandwich estimate  \hat{\bld{V}}^s_0=\bld{D}_0'\bld{D}_0 where  \bld{D}_0=\bld{U}_0\bld{I}_0^{-1}:

\hat{{\beta}_1} (\hat{\bld{V}}^s_0) ^{-1} \hat{{\beta}_1} &=& [\bld{I}_0^{-1} (... ...{1})] \ &=& (\bld{U}'_0\bld{1})' (\bld{U}_0' \bld{U}_0)^{-1} (\bld{U}'_0\bld{1})

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