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A trial was conducted at Stanford University to investigate the effectiveness of maintenance therapy for acute myelogenous leukemia (aml). After being treated by chemotherapy until remission, patients were randomized into two groups: one that received maintenance therapy and a control group that did not. The patients were observed until they suffered a relapse, the event of interest. The event time variable is the length of time in remission—the time from entry into the study (being randomized into a group) until relapse.

Use the Kaplan-Meier method to estimate proportion of patients in remission for each group. Carry out a test of equality over strata to Determine whether there is a significant difference in remission time between the patients who received maintenance therapy and those who did not.

SAS Institute Inc.

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The Aml_survival data set contains data about the efficacy of maintenance therapy for acute myelogenous leukemia (aml).

These are the variables in the data set:

This data is sample data from SAS Institute Inc.

The likelihood ratio test should be used if the distribution of the event times is found to be exponential. The results from both the log-rank and Wilcoxon tests suggest that the data does not indicate evidence that there is a difference in remission time between patients that received the maintenance therapy and those who did not.