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NLMIXED Procedure

The NLMIXED procedure fits nonlinear mixed models, that is, models in which both fixed and random effects enter nonlinearly. These models have a wide variety of applications, two of the most common being pharmacokinetics and overdispersed binomial data. PROC NLMIXED enables you to specify a conditional distribution for your data (given the random effects) having either a standard form (normal, binomial, Poisson) or a general distribution that you code using SAS programming statements. PROC NLMIXED fits nonlinear mixed models by maximizing an approximation to the likelihood integrated over the random effects.


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