The MODEL=INPUTNEVENTS option in the SAMPLESIZE statement specifies the number of events from a fixed-sample study of survival data. There are two new INPUTEVENTS options for the sample size computation: ACCRUAL= and LOSS=. The ACCRUAL= option specifies the method for individual accrual. The LOSS= option specifies the individual loss to follow-up in the sample size computation.

The STOP=BOTH option in the DESIGN statement specifies the condition of early stopping for the design. The new BETABOUNDARY=BINDING suboption computes the Type I error probability with the acceptance boundary, and the new BETABOUNDARY=NONBINDING suboption computes the Type I error probability without the acceptance boundary.