SEQTEST Procedure

The SEQTEST procedure is used in conjunction with the SEQDESIGN procedure to carry out interim analyses for clinical trials. At each stage, you analyze all the data available at that point with a statistical procedure and compute a test statistic and its information level. You then use the SEQTEST procedure to compare the test statistic with the boundary values for that stage. If the information levels of the data do not match the levels specified in the design, the SEQTEST procedure modifies the boundary levels appropriately. In addition, the SEQTEST procedure computes quantities such as average sample sizes, stopping probabilities, and conditional power. At the conclusion of the trial, the SEQTEST procedure computes parameter estimates, p-values, and confidence limits.