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The PHREG Procedure |
Let be the parameter vector. For the Cox model, the
’s are the regression coefficients
’s, and for the piecewise constant baseline hazard model, the
’s consist of the baseline hazards
’s (or log baseline hazards
’s) and the regression coefficients
’s. Let
be the chain representing the posterior distribution for
.
Consider a quantity of interest that can be expressed as a function
of the parameter vector
. You can construct the posterior distribution of
by evaluating the function
for each
in
. The posterior chain for
is
Summary statistics such as mean, standard deviation, percentiles, and credible intervals are used to describe the posterior distribution of
.
As shown in the section Hazard Ratios, a log-hazard ratio is a linear combination of the regression coefficients. Let be the vector of linear coefficients. The posterior sample for this hazard ratio is the set
.
Let be a covariate vector of interest.
Let be the observed data. Define
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Consider the th draw
of
. The baseline cumulative hazard function at time
is given by
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For the given covariate vector , the cumulative hazard function at time
is
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and the survival function at time is
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Let be a partition of the time axis. Consider the
th draw
in
, where
consists of
and
. The baseline cumulative hazard function at time
is
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where
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For the given covariate vector , the cumulative hazard function at time
is
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and the survival function at time is
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