Measures of Marker Informativeness

Polymorphism Information Content

The polymorphism information content (PIC) measures the probability of differentiating the allele transmitted by a given parent to its child given the marker genotype of father, mother, and child (Botstein et al. 1980). It is computed as

Heterozygosity

The heterozygosity, sometimes called the observed heterozygosity, is simply the proportion of heterozygous individuals in the data set and is calculated as

Allelic Diversity

The allelic diversity, sometimes called the expected heterozygosity, is the expected proportion of heterozygous individuals in the data set when HWE holds. It is calculated as