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Creating the Process Mixture Design

Since there are few standard designs accommodating mixture experiments with process variables, ADX uses the optimal design interface to construct the design. To generate the runs, do the following:

1. Click Select Design from the main design window.
2. The Optimal Design Creation window appears in place of the standard Design Selection window.
   
   

   
   
   

3. Select the model you want to use by clicking the down arrow beside Model. Select Mixture model, the only item on the menu.
4. The Model Specification window appears. Click the down arrow beside Select a model.
5. The pop-up menu lists all the possible choices for the number of factors you defined. Select Quadratic.
   
   

   
   
   

6. Click OK to change the model.
7. Change the number of runs to 25, if necessary.
8. You can review the candidate set or alter options in the design search algorithm, just as you did in Chapter 8, "Optimal Designs." However, the defaults are satisfactory in this case.
9. Close the Optimal Design Creation window and click Yes to generate the design. ADX searches for a -optimal design based on the model you defined.
   
   

   
   
   

At this point, you can enter the responses. Instead, close the design you just created and open an identical sample design called Tablet Formulation Mixture, which contains the responses.